ASTAXANTHIN REDUCES STEMNESS MARKERS IN BT20 AND T47D BREAST CANCER STEM CELLS BY INHIBITING EXPRESSION OF PONTIN AND MUTANT P53

Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53

Astaxanthin (AST) is a product made from marine organisms that has been used as an anti-cancer supplement.It reduces pontin expression and induces apoptosis in SKBR3, a breast cancer cell line.Using Western blotting and qRT-PCR analyses, this study revealed that in the T47D and BT20 breast cancer cell lines, AST inhibits expression of pontin and mu

read more

New Cheilostomata (Bryozoa) from NE Atlantic seamounts, islands, and the continental slope: evidence for deep-sea endemism

Ten new species belonging to three new genera (Atlantisina gen.nov., Bathycyclopora gen.nov., Calvetopora gen.nov.) of umbonulomorph bryozoans from northeastern Atlantic seamounts, islands, and the continental slope are introduced.We furthermore erect the new family Atlantisinidae fam.nov.for these genera.Eight new species belong to the new genus A

read more

SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function

Abstract Modelling insulin-glucose homeostasis may provide novel functional insights.In particular, simple models are THYROSMART clinically useful if they yield diagnostic methods.Examples include the homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI).However, limitations of these approaches have been

read more